Osmosis Jones isn't the funniest movie I have ever seen, but it is very clever and has an original concept. The humour is crude I agree, but it is actually amusing- the script does have its witty and amusing parts. The animation is not too bad either, certainly a unique style of animation, the backgrounds are nice and the characters have interesting features. And the music is very good as well. As I've said already, the concept is very original and the equally original and well written story(even with one or two predictable parts) does justice to that concept. Also, I liked the characters, Ozzy and Drix are likable and what they get up to is intriguing, fun and often unpredictable, Thrax is a great villain and the voice acting from Chris Rock, Laurence Fishburne, David Hyde Pierce, William Shatner and Bill Murray is top notch. Overall, clever, original and entertaining. 8/10 Bethany Cox

The Farrelly brothers are dipping into the animation pool. It's colorful and primitive animation. It's pretty good, but that's not really the problem. Surprisingly the problem is Bill Murray and live action stuff.

Frank Detomello is a slob. He eats a hard boiled egg covered with a deadly germ. And we travel inside Frank to see white blood cell policeman Osmosis Jones (Chris Rock) battle evil virus Thrax (Laurence Fishburne) with the help of Drix (David Hyde Pierce).

Bill Murray looks awful as he gets sicker and sicker. I have to ask if we're supposed to laugh at Bill? It's just gross. Not the gross out humor that the Farrellys are known for. It isn't funny at all.

The animated sections are much better. In fact I prefer they cut out the live action stuff. Chris Rock does a good voice. He has good chemistry with David Hyde Pierce's Drix. They need a few more jokes, but I like the City of Frank.

Frank (Bill Murray) is a widow without hygienic and bad alimentary habits. He eats food that felt on the floor without cleaning, he does not wash his hands before eating and he eats only junk food. His daughter keeps unsuccessfully trying to correct his behavior. One day, Frank eats a dirty egg and gets a disease. From this moment on, the human body functions are showed through very funny and educational cartoons. The hero, Osmosis Jones, is a white globule, with Chris Rock's voice. The great Farrely brothers again surprise me. This funny (and sometimes scatological movie) is a great class of hygienic and human body functions. Chris Rock and Laurence Fishburne give a great performance with their voices. Bill Murry has the role of a disgusting character. An excellent and very educational movie, indicated also (or specially) for children. My vote is nine.